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University of Tubingen PostDoc - Gene therapy of preleukemia syndromes 2025

 

We are seeking a highly motivated and skilled Postdoctoral Researcher to join our interdisciplinary team in the Division of Translational Oncology headed by Prof. Julia Skokowa. Our laboratory is dedicated to advancing the understanding of the molecular mechanisms of hematopoiesis, granulopoiesis, and leukemia development. We also develop innovative gene therapy approaches for hematopoietic stem cell disorders, with the ultimate goal of clinical translation.

Tasks:

  • Design and conduct in vitro and in vivo experiments using gene-edited hematopoietic stem/progenitor cells.
  • Develop and optimize gene editing protocols for ELANE for therapeutic use.
  • Evaluate safety, efficacy, leukemogenicity and off-target effects of gene therapies in preclinical models.
  • Actively participate in the development of GMP-compatible protocols for clinical translation.
  • Assist in the preparation of regulatory documents and collaborate with clinical and regulatory teams to support the transition to first-in-human trials.

Table of Content

Summary

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Benefits

  • A multicultural, multidisciplinary and highly motivated team
  • A dynamic and supportive research environment within a leading academic institution
  • Access to state-of-the-art facilities and technologies
  • Opportunities for professional development and career advancement, including access to the SPARK-BIH mentoring program and participation at national and international conferences
  • Close collaboration with clinical and translational research partners
  • Subsidy for public transportation tickets and employee discounts

Requirements

  • PhD or postgraduate degree with focus in cellular and molecular biology, gene editing, human stem cell biology, hematopoiesis and leukemogenesis
  • Experience with gene editing technology, HSC culture, and in vivo models of blood cell disorders is highly desirable
  • Experience in GMP production and clinical trial development is desirable
  • Excellent analytical, organizational, and communication skills
  • English proficiency required

Application Documents

  • CV including publication list,
  • Cover letter, and
  • References needed

Application Deadline

August 31, 2025

How To Apply

Are you qualified and interested in this opportunity? Kindly go to University of Tübingen on jobs.medizin.uni-tuebingen.de to apply

Contact for questions

  • Mrs. Dr. Patricia Arreba Tutusaus
    • 07071 29-68864

Online Application to

  • Mrs. Prof. Dr. med. Julia Skokowa, PhD
    • Index number: 6534

For more information, kindly visit University of Tubingen scholarship webpage.

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