We are seeking a highly motivated PhD student (f/m/x) with a strong interest in immunology, virology, and infectious diseases to join our Emmy Noether–funded translational research group. The project focuses on characterizing viral antibody resistance mechanisms in people living with HIV, combining patient-derived data with state-of-the-art experimental and computational approaches.
You will independently plan and execute a translational PhD project with direct clinical relevance. Your responsibilities include:
- Detection, analysis, and functional characterization of HIV-1 envelope sequences
- In vitro and in vivo testing of HIV-1 antibody sensitivity
- Analysis of HIV-1 sequence diversity and viral antibody resistance mechanisms
- Assessment of the impact of resistance-associated mutations on viral fitness
- Establishment and performance of immunological and virological assays, including:
- Primary cell work and cell culture
- Virus cultures
- PCR, cloning, and molecular biology techniques
- Flow cytometry, ELISA, immunohistochemistry
- Analysis of large viral sequence and phenotypic datasets
- Presentation of results at internal meetings and national and international conferences
- Preparation of manuscripts with the goal of publishing in high-impact international journals
Table of Content
Summary
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Benefits
- We offer a highly clinically relevant translational research project in a young research group and a stimulating and internationally highly competitive environment
- Freedom and the support to design, implement, and direct own research projects and strong promotion of professional development
- Full access to state-of-the-art technology platforms and facilities to carry out cutting edge translational research
- A constantly growing group of highly motivated researchers
- A wide range of advanced techniques in the field of molecular and cellular biology, virology, infectious diseases, and immunology
- Flexible working time models to support family life
Requirements
You are an enthusiastic early-career scientist with a strong academic background and curiosity-driven mindset:
- Excellent Master’s or Diploma degree in life sciences, medicine, or a related field
- Solid knowledge of immunology, virology, molecular biology, or related disciplines
- Strong scientific motivation and independence
- Ability to work effectively in a collaborative, interdisciplinary team
- Excellent English skills (spoken and written); German is desirable but not required
Application Documents
Please submit your application including:
- Detailed CV
- List of publications (if applicable)
- Contact details of two references
- Brief description of your research interests
Application Deadline
March 8, 2026How To Apply
For more information, kindly visit the University of Cologne website.
