The Emmy Noether-funded research group of Dr. Dr. med. Alexander Busch investigates the regulation of the hypothalamic-pituitary-gonadal (HPG) axis—a key system in human reproductive development and fertility. The group combines clinical cohorts, population-scale genetics, and molecular biology to understand how early life periods, such as minipuberty and puberty, shape reproductive capacity.
The position is embedded in the IMF-funded project “ANDROGEN”, which aims to functionally validate newly identified genetic variants that regulate quantitative spermatogenesis. This integrative project combines GWAS, bulk and single-cell transcriptomics, protein validation, and regulatory reporter assays.
Learn more about the group here.
YOUR MISSION:
- Investigate how genetic variants affect male reproductive function
- Perform single-nucleus and bulk RNA sequencing of testicular tissue
- Validate gene expression at the protein level via IHC and Western blotting
- Analyze large-scale transcriptomic data (R, Python)
- Test allele-specific regulatory activity using luciferase reporter assays
- Integrate omics data to identify functional variants affecting spermatogenesis
Table of Content
Summary
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Benefits
- A full 3-year PhD position within a dynamic Emmy Noether group
- A central role in a cutting-edge multi-omics project with direct translational relevance
- Individual mentoring, conference participation, and career development support
- A collaborative, international, and family-friendly work environment
Requirements
- A Master’s degree in Biology, Molecular Medicine, Biochemistry, Biotechnology, or a related discipline
- Solid wet-lab experience in molecular biology, ideally with tissue or protein work
- Motivation to develop bioinformatics and data analysis skills (training provided)
- Proficiency in English (spoken and written); German is a plus but not required
- Team spirit, communication skills, and scientific curiosity
- Prior experience with transcriptomics and/or reproductive biology
Application Documents
- A motivation letter describing your interest in reproductive biology and genomics
- A brief summary of your laboratory and/or analytical experience
- Your CV
- Names and contact details of 1–2 referees willing to provide a letter of reference
Check also:
2026 Fully Funded Humboldt Research Fellowship
2026 Konrad Adenauer Foundation Scholarship
Application Deadline
August 27, 2025How To Apply
Are you qualified and interested in this opportunity? Kindly go to
University of Münster on p78quickapply-r3jdhzllus.dispatcher.eu2.hana.ondemand.com to apply
For inquiries, please contact: Dr. Dr. med. Alexander S. Busch, [email protected]
For more information, kindly visit University of Münster scholarship webpage.
