University of Freiburg PhD Candidate in CRC1479 OncoEscape 2026

The Department of Pediatric Hematology and Oncology, Center for Pediatrics (medical director: Prof. T. Feuchtinger) has an opening in the field of novel cell, immune and gene therapies starting in Q1 2026 for a PhD candidate (Biology, Biochemistry, Molecular Medicine or related).

The University of Freiburg is seeking candidates with an interest in cancer immunology and pediatric oncology to conduct comprehensive in vitro and in vivo functional testing for prevention of immune escape. The available PhD project aims to investigate immune escape mechanisms of pediatric leukemias in the context of modern immunotherapies, particularly CAR T-cell therapies. The goal is to understand the biological basis of therapy-resistant relapses and to translate these findings into new, clinically relevant treatment strategies.

Methodological focus:

• Gene editing of human (stem) cells and CAR T cell generation (CRISPR/Cas, viral transduction)
• Cell culture and functional immune assays (eg, cytotoxicity and cytokine analyses)
• Multiparameter flow cytometry and molecular biology analyses
• Preclinical mouse models (xenograft and syngeneic CAR T cell models) for investigating immune escape and therapeutic response
• Analysis of primary patient samples

Table of Content

• Summary
• Benefits
• Requirements
• Application Deadline
• How To Apply

Summary

• Application DeadlineNot Specified
• Study LevelPhD
• SponsorUniversity of Freiburg
• City to studyBaden-Württemberg
• School to studyUniversity of Freiburg
• Eligible CountryAll Countries

Benefits

• PhD thesis within a collaborative research center (CRC1479 OncoEscape)
• Exceptional environment for translational immunology & oncology research
• Motivated team of lymphocyte engineers
• Modern laboratory with excellent infrastructure
• Widespread local, national and international collaborations

Requirements

• Master degree in biology, biochemistry, molecular medicine or related fields
• Strong background in cell biology, immunology and molecular biology
• Experience in and readiness to perform in vivo functional tests in mouse models
• Good command of spoken and written English

Check also:
2026 Fully Funded Humboldt Research Fellowship
2026 Konrad Adenauer Foundation Scholarship

Application Deadline

Not Specified

How To Apply

Are you qualified and interested in this opportunity? Kindly go to University of Freiburg on karriere.uniklinik-freiburg.de to apply

Contact: [email protected]

For more information, kindly visit University of Freiburg webpage.