Universitätsklinikum Frankfurt Master Thesis in Cancer Research – Department of Medicine 2, Hematology and Oncology 2025

The Department of Medicine 2, Hematology / Oncology at the Goethe University Hospital Frankfurt offers the entire spectrum of diagnostics and therapy of malignant diseases as well as a research program focusing on several cancer entities. The research laboratory of Professor Thomas Oellerich is part of the Frankfurt Cancer Institute and focuses on oncogenic signaling and therapy resistance mechanisms in lymphoma and acute myeloid leukemia.
The lab is furthermore funded by the German Cancer Consortium (DKTK), which was founded in 2012 as one of the six German Centers of Excellence for Health Research (DZG). DKTK aims at bringing promising results from cancer research faster into clinical development and patient care. In the DKTK more than 20 academic research institutions and university hospitals at seven partner sites cooperate with each other and the German Cancer Research Center (DKFZ) in Heidelberg as the core center (https://dktk.dkfz.de/standorte/frankfurt-mainz).

Your Role:

The project focuses on deciphering a novel cancer vulnerability in Lymphoma. The gene of interest is involved in ubiquitin-like protein (UBL) signaling that seems to influence B-cell development.

• Molecular biology tasks include Western Blotting, cell culture, DNA-damage and replication assays, flow cytometry and image-based assays.
• Genetic modification of cancer cell lines utilizing CRISPR-Cas9 and shRNA-mediated knockdowns
• State-of-the-Art advanced techniques such as proximity-labeling, MassSpec proteomics, RNAseq
• Data analysis, figure generation and scientific presentations

Table of Content

• Summary
• Benefits
• Requirments
• Application Deadline
• How To Apply

Summary

• Application DeadlineJuly 10, 2025
• Study LevelMasters
• SponsorUniversitätsklinikum Frankfurt
• City to studyHesse
• School to studyUniversitätsklinikum Frankfurt
• Eligible CountryAll Countries

Benefits

• Collective labour agreement  TV GU
• International and cosmopolitan working environment
• Excellent tandem supervision by a PhD student (Ria Mainkar) and a Team Leader (Dr. Ramesh K Krishnan)
• Scientific education including the management of scientific literature, a bi-weekly journal club, good scientific presentation and publication practice
• Uniklinik-Campus, Mensa, Cafés
• Insights: Instagram, YouTube, LinkedIn
• FAQ´s for new employees

Requirements

• Enrolled in a university master program in biology, biochemistry or a related discipline.
• Enthusiasm and fascination for biomedical research, oncology, cell and molecular biology.
• High motivation for experimental lab work.
• Experiences in cell and molecular biological as well as biochemical lab techniques might be of advantage.
• Ability to work in a team, sense of responsibility and proactivity.
• Basic knowledge in MS-Office (Word, Excel).
• Fluent in English.
• Due to legal regulations, valid proof of measles immunity / measles vaccination is required.

Application Deadline

July 10, 2025

How To Apply

Are you qualified and interested in this opportunity? Kindly go to Universitätsklinikum Frankfurt on jobdb.softgarden.de to apply

Contact: Dr. Niklas Dienstbier (Team Lead - Mechanistic Lymphoma Research)
Phone or Email: 069-6301-84001 or [email protected]

For more information, kindly visit Universitätsklinikum Frankfurt scholarship webpage.