The Institute for Experimental Immunology and Imaging, Department of Immunodynamics is seeking a Research Associate (Postdoc) for “MS-based single-cell and spatial multi-omics”.
Your tasks
- Measurement and analysis of data sets from liquid chromatographic mass spectrometry (LC-MS/MS) and imaging matrix-associated laser desorption/ionization mass spectrometry (MALDI-MSI).
- Establishment of multiplex IF microscopy staining and automated analysis of microscopic datasets using segmentation algorithms and AI
- Isolation of malignant tissue/cells by laser microdissection for further mass spectrometric investigations
- Application of light-sheet microscopy in combination with mass spectrometry
- Development of methods for "minimal proteic sample preparation"
- Establishment of bioinformatic algorithms for registering multi-omics approaches from mass spectrometric and microscopic datasets
- Integrative evaluation of the data using multivariate analyses, dimensionality reduction, and "pathway", "signaling" and "enrichment" analyses.
- Establishment of new machine learning algorithms to identify patterns in mass spectrometric and microscopic datasets
- Support of the working group "Single-cell and spatial multi-omics" with supervision of students and PhD students
Table of Content
Summary
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Benefits
- a highly motivated, international team
- an advanced scientific environment in immunodynamics
- the application of the latest technological approaches
- dynamic scientific exchange
- a high-resolution microscopy and mass spectrometry portfolio
- interdisciplinary and translational research with human samples
- Development of therapeutic approaches for targeted medicine
- A secure job in the public service of the state of North Rhine-Westphalia
- Fair pay according to the collective agreement (TV-L) including annual bonus and company pension scheme
- 30 days of vacation per calendar year (based on a 5-day work week)
- Interdisciplinary work with colleagues from other disciplines
- Working with modern equipment and certified quality standards
- Family-friendly corporate culture , e.g., company daycare, holiday program for school-age children, advice and support from the Family & Health department in all situations.
- Diverse training and further education opportunities , e.g. at the UK Essen training academy
- Health management , e.g., workplace reintegration management, vaccinations, promotion of sports programs
- Attractive additional benefits , e.g. discounted canteen meals, community events, dormitory places
Requirements
- Completed university degree (Master's or Diploma) in Chemistry, Physics, Molecular Biology, Biomedicine, Biology or a comparable field, as well as a completed doctorate.
- Excellent expertise in mass spectrometry
- They work independently/on their own responsibility and reliably.
- They are flexible, committed, and team players.
- They possess very good computer and English skills.
Desirable skills and skills to be developed as part of the job:
- Expertise in mass spectrometry, bioinformatics, microscopy and systems biology
- Analysis of microscopic and mass spectrometric datasets
- Integrative analyses via systems biology and pathway analyses
- Machine learning algorithms
- Software / Languages ??/ Applications: MS-Office, Spectronaut, DIA-INN, Proteome Discoverer, R, Python, Cytoscape, SkillsLab, String, GSEA
Check also:
2026 Fully Funded Humboldt Research Fellowship
2026 Konrad Adenauer Foundation Scholarship
Application Deadline
Not SpecifiedHow To Apply
For more information, kindly visit the Universitätsklinikum Essen webpage.
