The YF vaccine is the most successful live-attenuated vaccine available and provides long-lasting immune protection after a single dose, however the exact mechanisms governing its immunogenicity and efficacy remain to be fully elucidated. This PhD position is focused on investigating the spatial and temporal coordination of the early immune response to the live-attenuated yellow fever vaccine at the injection site in human skin using a multiomics approach including transcriptomics and targeted proteomics. A specific focus will be placed on cell-cell communication and antigen delivery to dendritic cells for initiating adaptive immunity as determinants of vaccine effectiveness involving primary cell culture experiments with dendritic cells. The project is integrated into the EU-funded Consortium Yellow4FLAVI "Deconstructing the protective immunity of yellow fever virus 17D to inform flavivirus vaccine design"
Your tasks and responsibilities:
- Design and perform experiments, analyze transcriptomic/multiomic data
- Keep up to date with project-related literature
- Contribute ideas to develop the research project
- Communicate and collaborate across disciplines and professional groups
- Actively participate in meetings, seminars and conferences
- Contribute to writing research manuscripts and reports
Table of Content
Summary
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Benefits
- An exciting project in an innovative and modern laboratory
- Excellent training and support in a motivated, international team
- Creative working conditions in a high-profile research environment
- Opportunity to obtain a PhD in Medical Research (structured program of the Munich Medical Research School)
- Participation in an international and interdisciplinary research project
- Free parking and good public transportation connections
- Numerous LMU employee benefits, e.g. discounted fitness and cultural offers, job public transport ticket, Jobbike as well as several canteens and cafés on campus
- Salary based on the TV-L scale (E13/65%)
We welcome applications from all backgrounds. The promotion of diversity is an important strategic goal at our center. This is reflected in the BMC Code of Conduct, which actively promotes diversity and equal opportunities.
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People with disabilities who are equally as qualified as other applicants will receive preferential treatment.
Requirements
- Master’s degree in Biology, Biochemistry, Immunology, Molecular Medicine or related natural science disciplines
- Scientific background in Immunology
- Practical experience in cellular and molecular biology and immunology techniques (flow cytometry and/or transcriptomics and/or bioimaging) desirable.
- Basic bioinformatics skills (R, Python) desirable; an aptitude to acquire necessary data analysis skills required
- Very good communication in English (spoken and written); basic knowledge of German desirable
- Organizational and team skills, flexibility, curiosity, responsible work ethics
- Passion for research with strong analytical and problem-solving skills
- Interest in working independently on scientific questions
Check also:
2026 Fully Funded Humboldt Research Fellowship
2026 Konrad Adenauer Foundation Scholarship
Application Deadline
January 15, 2026How To Apply
Please submit your complete application exclusively via our online application tool, including the following documents individually as pdf files:
- Cover letter describing briefly your motivation and qualification
- Curriculum Vitae (max. 2 pages)
- Short description of research projects carried out during your studies. Please describe the rationale of the research, and highlight your contributions to the results (approx. 300 words).
- Description of your general research interests and career goals (approx. 200 words).
- What do you find interesting about our research and this PhD position? (approx. 200 words).
- Updated Transcripts
- Contact details for at least two referees, including at least one direct supervisor who has worked with you for at least six months.
AI Policy: AI assistance is welcome for tasks like proofreading, but you must clearly mention where it was used. Primarily AI-generated applications will be automatically discarded without feedback
Applications will be considered if submitted by January 15th, 2026.
For more information, kindly visit LMU webpage.
