Published: 04 Feb 2026 11 views
Our group at Ruhr-University Bochum, Germany is striving to establish “unconventional” interactions like halogen bonding and chalcogen bonding in non-covalent organocatalysis. These interactions are conceptually similar to the well-known hydrogen bonding but feature some distinct advantages (e.g. “soft” interacting atoms and high directionality) and have been much less explored.
Your tasks:
The candidate will design and implement multi-step synthesis towards functionalized neutral or cationic halogen bond donors based on literature research and own method development. The synthesis of the target compounds will be characterized by NMR and various other spectroscopic techniques. As initial test of performance, binding constants to several substrates will be determined. Subsequently, reaction kinetics with appropriately chosen test reactions will be conducted to gauge catalyst performance. In addition, we will use some of the halogen bond donors for the construction of supramolecular assemblies in the solid state and in solution. An overview of halogen and chalcogen bonding organocatalysis can be found here: Angew. Chem. Int. Ed. 2024, e202404823.
Check also:
2026 Fully Funded Humboldt Research Fellowship
2026 Konrad Adenauer Foundation Scholarship
For more iformation, kindly visit the Ruhr University Bochum webpage.
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