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2025 PhD Student in Cancer Breaksome at DKFZ Germany

The Junior Research Group "Brain Mosaicism and Tumorigenesis" headed by Dr. Pei-Chi Wei is seeking for the next possible date a PhD Student in Cancer Breaksome.

Goals of the PhD Project

  • Map and classify RS-mediated and naturally occurring DSBs in distinct cancer cell types
  • Integrate multi-omics datasets (DSB maps, replication timing/direction, transcription orientation, and R-loop profiles) to identify cancer-type-specific vulnerabilities
  • Generate engineered cancer cell lines (in collaboration with a technician) and design hypothesis-driven analyses to identify targetable mechanisms of genomic instability
  • Contribute to developing reverse-translational strategies for therapeutic interventions in osteosarcoma and breast cancer

Table of Content

Summary

  • Application DeadlineNovember 11, 2025
  • Study LevelPhD
  • SponsorGerman Cancer Research Center (DKFZ)
  • Eligible CountryAll Countries
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Benefits

  • Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level
  •  Access to international research networks
  •  Doctoral salary with the usual social benefits
  •  30 days of vacation per year
  •  Flexible working hours
  •  Possibility of mobile work and part-time work
  •  Family-friendly working environment
  •  Sustainable travel to work: subsidized Germany job ticket
  •  Unleash your full potential: targeted training and mentoring through the DKFZ International PhD Program and DKFZ Career Service
  •  Corporate Health Management Program offers a holistic approach to your well-being

Requirements

  • Major in biology, bioinformatics, or related fields (genetics, genomics, bioengineering, applied mathematics)
  • Obtained or will obtain a Master’s degree in the above fields
  • (For biologists) Intermediate programming skills in R or Python and prior experience analyzing omics datasets are advantageous
  • (For bioinformatic-mathematic trait) Good performance in biology courses at university
  • Proficient in English (spoken and written)
  • Self-motivated, committed, and capable of independent as well as collaborative work

Note: The PhD project will focus on computational and experimental analyses of cancer cell lines; animal experiments will be performed by collaborating labs.

 

Application Documents

Interested candidates should submit:

  • CVcover letter,
  • Academic transcripts, and
  • Contact details of two references

Application Deadline

November 11, 2025

How To Apply

Are you qualified and interested in this opportunity? Kindly go to German Cancer Research Center (DKFZ) on jobs.dkfz.de to apply

Contact: Dr. Pei-Chi Wei

  • Phone: +49 6221/42-3251

For more information, kindly visit DKFZ scholarship webpage.

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