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PhD Student in Signal Transduction in Human Sperm at the University of Münster 2026

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The central objective is to elucidate the genetic, molecular, and cellular mechanisms governing the formation and function of the testis, production and function of sperm, fertilisation, as well as early embryonic development – in both health and disease. To this end, we combine interdisciplinary research in molecular, structural, and cell biology as well as in physiology, biophysics, epi /genetics, (bio)informatics, and multimodal data analysis.

In this project, we will elucidate the molecular mechanisms that enable sperm to sense their chemical and physical environment, with a particular focus on ion channels and signalling molecules, proteins, and pathways.

 RESPONSIBILITIES:

  • Analyse the composition, physiological function, and pathophysiological relevance of Ca2+-signalling pathways in human sperm
  • Perform high time-resolution recordings of signalling events in the sperm flagellum using rapid-mixing techniques and fluorescent probes
  • Dissect the interplay of flagellar ion channels during chemosensory signalling with pharmacological tools
  • Participate in the Integrated Research Training Group ‘Reproduction.MS PhD-Training Centre in Translational Science’

Table of Content

Summary

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Benefits

  • State-of-the-art techniques, tools and experimental models for research
  • Competitive, interdisciplinary, creative, and international research environment with a track record of intense mutual collaboration
  • Structured PhD-training programme with a wide range of professional development opportunities
  • Salary according to tariff agreement, extra annual payment, and company pension plan (VBL)
  • A respectful and appreciative work environment within a diverse team

Requirements

  • Master’s degree in biology, biochemistry, pharmacy, physics, biomedicine, or other life sciences
  • Strong interest in cellular signal transduction
  • Experience in the use of fluorescent probes to study cellular signalling events
  • Knowledge on basic pharmacological principles
  • High motivation for scientific work and willingness to contribute to an interdisciplinary team
  • Commitment to research in a translational setting
  • Excellent English communication skills (spoken and written); German skills are advantageous

Application Documents

Please include:

  • Letter of motivation (max 2 pages)
  • Summary of your Master‘s thesis (max 1 page)
  • Transcript and scanned copies of your degree certificates
  • Two letters of recommendation
  • CV

Check also:
2026 Fully Funded Humboldt Research Fellowship
2026 Konrad Adenauer Foundation Scholarship

Application Deadline

Not Specified

How To Apply

For more information, kindly visit the University of Münster website.

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