Published: 30 Dec 2025 8 views
SFB/TRR 425 DEFINE brings together leading scientists in medicine (dermatology, pediatrics, internal medicine and surgery), molecular biology, immunology, biomedicine, and systems research to investigate fundamental mechanisms underlying development of diseases related to desmosome disorders. Within the scope of this SFB/TRR several projects of the Department of Vegetative Anatomy of the LMU in Munich were approved. Our group is dedicated to the characterization of desmosomal adhesion in the skin and investigation of mechanisms that contribute to loss of intercellular adhesion in the bullous autoimmune disease pemphigus. The hiring SFB/TRR project, led by Franziska Hartig-Vielmuth, member of the steering committee of the SFB/TRR, will work on the project B05 entitled: “Hyper-adhesion and mechanical stress to treat pemphigus”.
In this project, we will investigate how desmosomes mature and how, during that process, their adhesive properties are regulated. In addition, we aim to elucidate the role of mechanical stress on loss of keratinocyte adhesion in pemphigus. For this purpose, we will use a broad range of methods with a focus on biophysical methods (atomic force microscopy, cytostretcher) and imaging (STED microscopy). The main goal is to find common regulators of adhesive properties during maturation and in pemphigus, which can contribute to the development of novel therapeutic strategies in pemphigus.
Your tasks and responsibilities:
The position is limited in duration in accordance to the funding period for 3 years and 9 months. The application for prolongation of the consortium is planned.
We strongly encourage application of females.
People with disabilities who are equally as qualified as other applicants will receive preferential treatment.
Start date: 01.04.2026
Check also:
2026 Fully Funded Humboldt Research Fellowship
2026 Konrad Adenauer Foundation Scholarship
For more information, kindly visit LMU scholarship webpage.
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